The Importance of Screening in Congenital Hypothyroidism
نویسندگان
چکیده مقاله:
Introduction: Congenital hypothyroidism is the most common cause of preventable mental retardation in children. However, early diagnosis and treatment improve the prognosis of mental retardation. Clinical diagnosis of Congenital hypothyroidism is not also evident in the neonatal period. Therefore, screening all newborns for early diagnosis and treatment is essential. This paper aimed to analyze the results of neonatal screening at Mashhad University of Medical Sciences. Methods: This cross-sectional study included all newborns who admitted in Mashhad hospitals From March 20, 2012 to March 19, 2013. Overall, 104,399 cases referred to healthcare centers, and the soles of the feet were screened for congenital hypothyroidism. In this study, all the neonates were screened. Results: Overall, 48% of the patients were females. Also, 82.6% of the samples were obtained within 3-5 days of birth and the rest after 5 days. Based on the experimental results, 95.2%, 4.6%, 0.2%, and 0.1% of the newborns had thyroid stimulating hormone (TSH) level of 20 mu/L, respectively. After the second test, 229 patients (prevalence=2 per 1000 live births) were treated based on the diagnosis of congenital hypothyroidism, and 84.7% of the cases were treated while they were less than 28 days of age. Conclusion:Based on these results and the importance of rapid diagnosis and initiation of treatment in infants with congenital hypothyroidism, it is necessary to raise public awareness, encourage parents, and use the potential of other organizations and agencies.
منابع مشابه
The Importance of Examining Congenital Hypothyroidism in Connection with Congenital Heart Disease: Letter to Editor
Dear Editor-in-Chief: I read and enjoyed your stylish article, "Frequency of Congenital Cardiac Malformations in Neonates with Congenital Hypothyroidism", in relation to heart disease with hypothyroidism. As we know, one of the most commonly associated congenital hypothyroidism disorders is congenital heart disease, which has a significant effect on the recovery of pat...
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Background & Aims: Congenital hypothyroidism (CH) is one of the most common preventable causes of mental retardation throughout the world. The aim of this study was to investigate the prevalence of CH among newborns of East Azerbaijan province in 2009-2010. Methods: This descriptive analytic study was performed by using census cross- sectional method on 62459 neonates in East Azerbaijan pro...
متن کاملScreening for congenital hypothyroidism.
OBJECTIVE To review the screening program for congenital hypothyroidism in the Riyadh Al-Kharj Hospital Programme, Riyadh, Kingdom of Saudi Arabia, and to investigate the clinical and biochemical characteristics of affected infants. METHODS The study was carried out from 1985 to 2000 in the Clinical Chemistry Division, Department of Pathology, Riyadh Armed Forces Hospital, Kingdom of Saudi Ar...
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متن کاملCongenital hypothyroidism missed on screening.
Three patients with congenital hypothyroidism missed on routine screening due to normal low thyrotrophin concentrations in the neonatal period presented in later childhood. Clinicians should remain aware of hypothyroidism as a cause of morbidity in early childhood despite a national screening programme.
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عنوان ژورنال
دوره 5 شماره Abstract
صفحات 6- 7
تاریخ انتشار 2014-10-01
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